Adaptive immune responses serve as a key defense mechanism for the control ofinfections in vertebrates. Immune responses must be of sufficient strength tocontain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanismsof these molecules. Adaptive immune responses serve as a key defense mechanism for the controlof infections in vertebrates. Immune responses must be of sufficient strengthto contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatorymolecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.
- ISBN: 978-3-642-19544-0
- Editorial: Springer Berlin Heidelberg
- Encuadernacion: Cartoné
- Páginas: 150
- Fecha Publicación: 01/04/2011
- Nº Volúmenes: 1
- Idioma: Inglés