Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, this book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. Highlights the need for adoption of sustainable and green chemistry pathways in drug developmentReveals risk factors associated with the drug development process and the ways sustainable approaches can help address theseIdentifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability INDICE: 1. Introduction to Green and Sustainable Approaches in Medicinal Chemistry2. Controlled Release of Nanodrugs: a Biosafe Approach3. Risk Factors in Drug Development Process4. Green Biomaterials for Tissue Engineering5. Flavonoids Encapsulated Nanomaterials for Medical Applications6. Green chemistry in the development of anti-infective agents7. Green chemistry in the development of CNS active agents8. Natural spices in medicinal chemistry: Isolation, Chemistry and Biology9. The role of ionic liquid in medicinal chemistry10. Hormones and Contraceptives11. Drug design through the Computational tools12. Drug synthesis and Development Using Green Chemistry13. Synthesis of Nitrogen-Oxygen Heterocycles by Sustainable Nanocatalysis14. Antibacterial and antimicrobial coating on metal substrate by spraying: present and future perspective15. Green Chemistry Approach Towards New Drug Development16. Microwave-Assisted Sustainable Medicinal Chemistry

• ISBN: 978-0-12-817592-7
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 610
• Fecha Publicación: 10/01/2020
• Nº Volúmenes: 1
• Idioma: Inglés