Pan-genomics: Applications, Challenges, and Future Prospects

Pangenomics and the evolution of bacteria: an overview of current approaches, challenges and future prospects is a detailed work on the current approaches and future applications of pangenomics. It covers the bioinformatics tools as well as their applications, and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided in three sections: the first, Overview of pangenomics and common approaches?, brings the main concepts and current approaches on pangenomics research; the second, Case studies in pangenomics?, discusses through twelve case studies the tools applied and the results gathered; and the last, Current approaches and future prospects in pan-multiomics?, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relation with human health. Covers the entire spectrum of pangenomics highlighting the use of specific approaches, case studies and future perspectivesDiscusses current bioinformatics tools and strategies for exploiting pangenomics dataPresents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability INDICE: Section 1. Overview of Pangenomics and common approaches 1. What is pangenomics? 2. Closed or Open Pangenome? 3. Orthology prediction in Pangenomics 4. Phylogenomics and molecular epidemiology in Pangenomics 5. Genomic Plasticity in Pangenomics 6. Reverse Vaccinology in Pangenomics 7. Drug target identification in Pangenomics 8. Software for Pangenomic analyse Section 2. Case studies in Pangenomics 9. Pangenomics of Organism 1 10. Pangenomics of Organism 2 11. Pangenomics of Organism 3 12. Pangenomics of Organism 4 13. Pangenomics of Organism 5 14. Pangenomics of Organism 6 15. Pangenomics of Organism 7 16. Pangenomics of Organism 8 17. Pangenomics of Organism 9 18. Pangenomics of Organism10 19. Pangenomics of Organism 11 20. Pangenomics of Organism 12 Section 3. Future perspectives 21. Pantranscriptomics 22. Panproteomics 23. Panmetabolomics 24. Panmetagenomics 25. Paninteratomics

• ISBN: 978-0-12-817076-2
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 600
• Fecha Publicación: 10/01/2020
• Nº Volúmenes: 1
• Idioma: Inglés