Competing risks and multistate models with R

This book covers competing risks and multistate models, sometimes summarized as event history analysis. These models generalize the analysis of time to a single event (survival analysis) to analysing the timing of distinct terminal events (competing risks) and possible intermediate events (multistate models). Both R and multistate methods are promoted with a focus on nonparametric methods. This book enables the reader to analyse complex time-to-event data himself, using the free open source language R for statistical computing. The data situations considered are competing risks--several, mutually exclusive event types and multistate models, that track an individuals history through different stages over time. These methods are a generalization of the now classical survivalanalysis--the analysis of time to one single event. Such data occur in a variety of fields, including life sciences, social sciences, economics and engineering. The methods are explained on a non-technical level and instantly carried out in R. This book covers data structures, simulating data, analyses of real life data and plotting. INDICE: Data examples. An informal introduction to hazard-based analyses. Competing risks. Multistate modelling of competing risks. Nonparametric estimation. Proportional hazards models. Nonparametric hypothesis testing. Further topics in competing risks. Multistate models and their connection to competingrisks. Nonparametric estimation. Proportional transition hazards models. Time-dependent covariates and multistate models. Further topics in multistate modeling.

• ISBN: 978-1-4614-2034-7
• Editorial: Springer New York
• Encuadernacion: Rústica
• Páginas: 245
• Fecha Publicación: 28/12/2011
• Nº Volúmenes: 1
• Idioma: Inglés