Cord blood is a significant source of hematopoietic stem and progenitor cellsfor the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. First book to discuss the transfusion potential of cord blood Collection of articles by global experts in the area of cord blood stem cell biology Includes preliminary clinical trials with cord blood that have been recorded and analysed Explores the futuristic use of cord blood in engineering applications like surgical stents and implants Discusses the potential use of cord blood in ischemic stroke INDICE: Placenta and Pregnancy Stem Cell.- Cord Blood Stem Cells-The BasicScience.- Ex Vivo Expansion of Cord Blood.- Gene Expression Profiling in CordBlood and Gene Integration Mapping in Peripheral Blood.- Hematopoietic Stem Cells from Umbilical Cord Blood.- To Characterize Mesenchymal Stromal Cells (MSC) Derived from Cord Blood in Comparison to the Classical Bone Marrow Derived MSC and also with Adipose Tissue Derived MSC.- Cord Blood Mesenchymal Stem Cell.- Double Cord Blood Transplants.- Cord Blood Transplantation for Paediatric Non-Malignant Condition.- Cord Blood Transplantation for Hematologic Malignancies.- Possibilities of Using Cord Blood for Improving the Biocompatibility of Implants.- Use of Cord Blood Stem Cells in the Interphase to Improve the Bio-friendliness of Ceramic Implants.
- ISBN: 978-1-84800-166-4
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 425
- Fecha Publicación: 01/09/2008
- Nº Volúmenes: 1
- Idioma: Inglés