The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSC Central Nervous System Disease Modeling, Volume 6 addresses how important induced pluripotent stems cells are and how they can be used to model CNS disorders. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions impossible before for some human diseases. This volume addresses central nervous system disease modeling, such as: Leber's hereditary optic neuropathy, autism, spinal muscular atrophy, Alzheimer's disease, ALS and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeuticsCovers how iPSCs can be used to model CNS disordersContributed by world-renown experts in the field INDICE: 1. In vitro human stem cell mediated CNS platforms: Progress and challenges 2. iPSCs for Modeling of X-linked dystonia-parkinsonism 3. iPSCs for Modeling of Leber's hereditary optic neuropathy 4. iPSC-based modeling in psychiatric disorders: Opportunities and Challenges 5. iPSCs for Modeling of hereditary spastic paraplegia 6. iPSCs for Modeling of Autism 7. iPSCs for Modeling of Spinal Muscular Atrophy 8. iPSCs for Modeling of Alzheimer's Disease 9. iPSCs for Modeling of ALS 10. Studying Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease with iPSCs 11. iPSCs for modeling Angelman syndrome 12. In Vivo Phenotyping of Familial Parkinson's Disease with iPSCs 13. iPSCs for Modeling Schizophrenia 14. iPSCs for Modeling Neurodevelopmental Disorders 15. iPSCs for Modeling of Multiple Sclerosis 16. Modeling developmental changes in HD using iPSCs
- ISBN: 978-0-323-85764-2
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 300
- Fecha Publicación: 01/05/2021
- Nº Volúmenes: 1
- Idioma: Inglés