It is essential to understand how stem cells interact with their microenvironment, the so-called stem cell niche, to establish and maintain their function. In this series, Advances in Stem Cells and their Niches, each volume will focus on an individual organ, looking at the stem cells in the organ itself, (if they exist), the niches and how to use them, alongside relevant methods and protocols. The Series will address stem cells during development, homeostasis and disease/injury of the respective organ. Advances in Stem Cells and their Niches will address new developments in the field including new data on disease, and clinical applications. Video content will illustrate such areas as protocols, transplantation techniques and work with mice. Explores not only reviews of research but also shares methods, protocols and transplantation techniques Contains Video content to illustrate such areas as protocols, transplantation techniques and work with mice Each volume concentrates on one organ making this a unique publication INDICE: Stroma cell niche regulation during HSC developmentCharles DurandHSC regulation by the bone marrow nicheLinheng Li and Pengxu Qian The role of the CNS in the regulation of HSCSimón Méndez FerrerImaging the Hematopoietic Stem Cell nicheCristina Lo CelsoNormal and malignant mature B cell nichesKarin TarteMechanisms of getting HSC in and out of the BM nicheTsvee LapidotAlterrations of HSC niche in myeloid malignanciesMarina KonoplevaTargeting the bone marrow niche in haematological malignanciesDaniela Krause
- ISBN: 978-0-12-811375-2
- Editorial: Academic Cell
- Encuadernacion: Rústica
- Páginas: 300
- Fecha Publicación: 01/04/2017
- Nº Volúmenes: 1
- Idioma: Inglés