Antidiabetic Drug Discovery from Natural Products

Antidiabetic Drug Discovery from Natural Products provides up-to-date and in- depth information, practical understanding and guidance in a comprehensive, systematic and easy-to-understand manner to scientists, researchers, graduate students on important and emerging biochemical topics related to current antidiabetic drug discovery research. This book analyzes and studies natural active substances and their medicinal chemistry in preventing and treating diabetes and its complications. It covers a wide range of critical issues to assist chemists in the discovery and development of safer, more affordable treatments, from identifying promising leads from medicinal plants to the extraction and synthesis of bioactive compounds. Following an introduction to bioactive chemical compounds from plants with antidiabetic effects, Antidiabetic Drug Discovery from Natural Products” describes the discovery and extraction of antidiabetic drugs and antioxidants from natural sources. It also examines antidiabetic plants before delving deeper into the chemistry behind major medicinal substances and their derivatives like Mangiferin and Resveratrol, discussing current and prospective uses. It intends to support and inspire medicinal chemists who are exploring natural sources as a starting point for creating standardized, safe, and effective antidiabetic therapies. Covers the history and current trends in antidiabetic natural product researchFocuses on each class of natural products, and their therapeutic effects on diabetesAnalyzes specific roles of different plant metabolites in the treatment of diabetes INDICE: Section 1: Putative antidiabetic drugs1. Natural products in antidiabetic drug discovery: Historical perspective2. Natural products in antidiabetic drug discovery: advances and opportunitiesSection 2: Plant bioactives and their antidiabetic potential3. Antidiabetic flavonoids from plant source4. Antidiabetic terpenoids from plant source5. Antidiabetic potential of plant alkaloids6. Antidiabetic carbohydrates from natural sources7. Antidiabetic potential of glycosides8. Antidiabetic potential of tannins9. Biological macromolecules as antidiabetic agents10. Antidiabetic drugs from fungi11. Antidiabetic secondary metabolites from marine sourceSection 3: Pharmacological mechanism12. Screening of antidiabetic drugs: in-vitro approaches13. Animal models for screening of antidiabetic drugs from natural sources14. Molecular Mechanisms of secondary metabolites as antidiabetic agents15. Network pharmacology approach for antidiabetic drugs from natural sourcesSection 4: Natural antidiabetics: Nature to clinic and market16. Recent advances in natural antidiabetics17. Antidiabetic drugs: Marketed formulations and case studies18. Antidiabetic drugs: Patent case studies19. Natural antidiabetic herbs and drug interactions

• ISBN: 978-0-443-30086-8
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 500
• Fecha Publicación: 01/02/2025
• Nº Volúmenes: 1
• Idioma: Inglés