Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals

Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals is a unique reference that provides a complete overview of the non-vitamin micronutrients, including calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc. In addition, the book covers the nutritional and toxicological properties of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, as well as ultra-trace minerals and those with no established dietary requirement for humans. Users will find in-depth chapters on each essential mineral and mineral metabolism, along with discussions of dietary recommendations in the United States and around the world. Presents the only scientific reference to cover all of the nutritionally relevant essential major and trace mineralsProvides a broad introductory chapter on each mineral to give readers valuable background and context Clarifies the cellular and molecular aspects of each mineral and its genetic and genomic aspectsIncludes coverage of all nutritionally relevant minerals-essential major trace minerals and ultra-trace mineralsUnderscores the important interactions between minerals so readers learn how metabolism of one mineral influences another INDICE: Calcium 1. Calcium-Sensing Receptor Polymorphisms and Human Disease 2. Molecular Aspects of the Calcium-Sensing Receptor and Calcium Hemeostasis 3. New Developments in our Understanding of the Regulation of Calcium Homeostasis by Vitamin D 4. Calcium in obesity and related diseases: the Calcium sensing receptor as a novel mediator 5. Calcium: Basic Nutritional Aspects 6. Molecular Aspects of Calcium and Bone Mineralization Copper 7. Copper: Basic Nutritional Aspects - To Be Submitted 8. Copper and Molecular Aspects of Cell Signaling 9. Copper and HIF Regulation of Gene Expression 10. Copper in Wilson's and Alzheimer's Diseases, Copper-Lowering Therapy in Cancer and Other Diseases, and Copper Deficiency Iodine 11. Iodine: Basic Nutritional Aspects 12. Iodine and Thyroid Hormone Synthesis, Metabolism and Action 13. Iodine and Adipocytokines: Cellular Aspects Iron 14. Iron: Basic Nutritional Aspects 15. Hepcidin and hormonal control of iron hemeostasis 16. Genetic Rodent Models of Systemic Iron Homeostasis 17. Iron, Cancer, and HIF Signaling 18. Iron Transporters and Iron Homeostasis 19. Regulation of DMT1 Expression and Function Zinc 20. Discovery of Zinc for Human Health and Bio-markers of Zinc Deficiency 21. Zinc Signals and Immune Function 22. Post-Translational Mechanisms of Zinc Signalling 23. Zinc Transporters in Health and Disease 24. Genetic study of zinc transporters and zinc signaling Magnesium 25. Magnesium: Basic Nutritional Aspects  26. Magnesium and the Immune Response 27. Magnesium Intake and Chronic Disease in Humans 28. Magnesium and Embryonic Development 29. Magnesium, Vascular Function and Hypertension - Revision under review Manganese 30. Nutritional, genetic and molecular aspects of manganese intoxication 31. Manganese and Nutritional Immunity 32. Manganese and Mitochondrial Function Molybdenum 33. Molybdenum cofactor in humans: health disease and treatment Phosphorus 34. Phosphorus: Basic Nutritional Aspects 35. Molecular Mechanisms of Adverse Health Effects Associated with Excess Phosphorus Intake 36. Transcriptional Regulation of Sodium-Phosphate Cotransporter Gene Expression Selenium 37. Selenium: Basic Nutritional Aspects 38. Selenium and Cancer 39. Could Selenium Be A Double-Edged Sword? Electrolytes 40. Sodium: Basic Nutritional Aspects 41. Potassium Channel Mutations and Human Disease: Focus on Adrenal Hypertension Non-Essentials 42. Chromium: Basic Nutritional and Toxicological Aspects 43. Non-Essential Trace Minerals: Basic Nutritional and Toxicological Aspects 44. Fluoride: Intake and Metabolism; Therapeutic and Toxicological Consequences

• ISBN: 978-0-12-802168-2
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 576
• Fecha Publicación: 01/10/2016
• Nº Volúmenes: 1
• Idioma: Inglés