Fragment-based drug discovery and x-ray crystallography

Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson .Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle.Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard.Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford.Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber.Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen.Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold.Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan. INDICE: D. A. Erlanson.Introduction to Fragment-Based Drug Discovery.- .T.G. Davies.Ian J. Tickle.Fragment Screening Using X-Ray Crystallography.- .S. Roughley.L. Wright.P. Brough.A. Massey .R. E. Hubbard.Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening.- .D. F. Wyss.Y.-S. Wang.H. L. Eaton.C.Strickland.J.s H. Voigt.Z. Zhu .A. W. Stamford.Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors.- .M. Hennig.A. Ruf .Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery.- .E. Valkov.T. Sharpe.M. Marsh.Sa. Greive .M. Hyvönen.Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery.- .J.h D. Bauman.D. Patel .E. Arnold.Fragment Screening and HIV Therapeutics.- .D. Rognan.Fragment-Based Approaches and Computer-Aided Drug Discovery.

• ISBN: 978-3-642-27539-5
• Editorial: Springer
• Encuadernacion: Cartoné
• Fecha Publicación: 23/01/2012
• Nº Volúmenes: 1
• Idioma: Inglés