This new volume of Advances in Pharmacology presents pharmacology of the blood brain barrier, focusing on targeting CNS disorders. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Contributions from the best authors in the fieldAn essential resource for pharmacologists, immunologists, and biochemists INDICE: I. Pharmacology of Transporter Targeting at the Blood Brain Barrier. 1. ABC transporter regulation by signaling at the BBB: Effect on Pharmacology2. P-glycoprotein trafficking as a therapeutic target to optimize CNS drug delivery3. Potential Role of Drug Transporters in Glial Cells on Drug Delivery to the CNS4. Blood Brain Barrier Na Transporters in Ischemic Stroke5. Transcytosis at the BBBII. Pharmacology of Therapeutic Targeting of Disease States. 6. Drug delivery to the ischemic brain7. Delivery of chemotherapeutics across the blood-brain barrier: Challenges and advances8. Delivery of anti-human African Trypanosomiasis (HAT) drugs across the blood-brain and blood-CSF barriers9. Delivery of therapeutic peptides and proteins to the CNS10. Engineering and pharmacology of blood-brain barrier-permeable bi-specific antibodies11. Pharmacological significance of prostaglandins transport at the brain barriers12. Hormonal influences on drug delivery to the CNSIII. Pharmacology of Targeting Complex Co-Morbidities. 13. BBB and hemorrhagic transformation after stroke14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood Brain Barrier in a Complex Neurological Disease15. Drug abuse and the neurovascular unit
- ISBN: 978-0-12-800282-7
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 520
- Fecha Publicación: 01/10/2014
- Nº Volúmenes: 1
- Idioma: Inglés