The Zebrafish: Disease Models and Chemical Screens

The Zebrafish: Disease Models and Chemical Screens, Fourth Edition, the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, developmental epigenetics, and the zebrafish interactome. Covers sections on model systems and functional studies, imaging-based approaches, and emerging studiesIncludes chapters written by experts in the fieldContains cutting-edge material on the topics discussed INDICE: 1. Analysis of Myelinated Axon Formation in Zebrafish Sarah C. Petersen and Kelly Monk 2. In vivo Analysis of White Adipose Tissue in Zebrafish John F. Rawls and James Minchin 3. Innate Immune Cells and Bacterial Infection in Zebrafish Jonathan Astin and Chris Hall 4. Study of Host-Microbe Interactions in Zebrafish Karen Guillemin and John F. Rawls 5. Infectious Disease Models in Zebrafish Carol Kim 6. Tumor - Host Innate Immune Cell Interactions in the Zebrafish Yi Feng 7. Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells Thomas Boehm 8. Hematopoietic Stem Cell Development: using the zebrafish to identify extrinsic and intrinsic mechanisms regulating hematopoiesis Trista E. North 9. Zebrafish as a Model for Hemorrhagic Stroke Brant M. Weinstein 10. Zebrafish Models of Sarcoma David Langenau 11. Iron Disorders Barry H. Paw 12. Regenerative Biology of Zebrafish Tendons Jenna Galloway 13. A Zebrafish Model for VHL and Hypoxia Signaling Freek van Eeden 14. Zebrafish Provides a Novel Model for Lymphatic Vascular Research Stefan Schulte-Merker 15. Small Teleost Fish Provide New Insights into Human Skeletal Diseases Paul Eckhard Witten 16. Zebrafish Models of Human Vision and Hearing Diseases Monte Westerfield 17. Zebrafish Muscular Dystrophy Models Peter Currie and Sharon Amacher 18. Liver Diseases Wolfram Goessling 19. A Zebrafish Xenograft Model for Studying Human Cancer Stem Cells Ewa Snaar-Jagalska and Lanpeng Chen 20. Analysis of Microglial Interactions with Brain Tumors in Zebrafish Dirk Sieger 21. Analysis of Pancreatic Disease in Zebrafish Mary Kinkel 22. Transplantation in Zebrafish Leonard I. Zon 23. Chemical Screening in Zebrafish for Novel Biological and Therapeutic Discovery Leonard I. Zon 24. Intestinal Disorders Michael Pack 25. Zebrafish Models of Leukemia Thomas Look

• ISBN: 978-0-12-803473-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 362
• Fecha Publicación: 01/02/2017
• Nº Volúmenes: 1
• Idioma: Inglés