Inflammation is a biological response triggered by different stimuli that has in the body a potentially damaging effect. In certain conditions, such as injury or infection, inflammation is a normal, healthy response. However, inflammatory disorders that result in the immune system attacking the body's own cells or tissues may cause abnormal inflammation, which results in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Mechanisms involved in promoting a number of different inflammatory disorders and their targeting for therapeutic benefit have been one of the hottest topics in last few decades. The two consecutive volumes (119 and 120) dedicated to this subject cover a wide spectrum of inflammatory disorders, mechanisms that are believed to cause them and different strategies for managing the inflammatory diseases. The volume integrates methods for studying inflammatory disorders, mechanisms that trigger these disorders and strategies for managing the inflammatory disordersIt contains timely chapters written by well-renown authorities in their fieldThe information provided in the volume is well supported by a number of high-quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students INDICE: 1. Novel anti-inflammatory therapeutics from nature Shoumo Bhattacharya 2. Biological functions and clinical implications of interleukin-34 in inflammatory diseases Yong-ming Yao 3. Pattern recognition receptor pathways as potential drug targets in inflammatory disorders Declan McKernan 4. Glycosylation changes in inflammatory diseases Philippe Delannoy 5. Inflammatory Bowel Disease and Targeted Oral Anti-TNF? Therapy Owen Rees Griffiths 6. The interplay between inflammation and cancer Ashok K. Munjal 7. Microglial NLRP3 inflammasome activation in Multiple sclerosis Kursad Genc 8. Sleep Deprivation, Oxidative Stress and Inflammation Samina Salim
- ISBN: 978-0-12-816844-8
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 264
- Fecha Publicación: 01/02/2020
- Nº Volúmenes: 1
- Idioma: Inglés