Protein-Protein Interactions in Human Disease, Volume 111, Part B promotes further research and development in the protein interaction network in order to identify critical proteins involved in the etiology of human diseases and locate new protein targets for drug development. Thus, this volume is of considerable interest to protein chemists, pharmacologists, cell biologists, immunologists, structural biologists, computational biochemists and other researchers working in the field. In addition, these articles would be of great benefit to medical, biology and pharmacology students who specialize in this field. Describes advances in the application of powerful techniques in studying and analyzing protein-protein interactionsIdeal for a wide audience of researchers, specialists and studentsWritten by authorities in their fieldContains a number of high quality illustrations, figures and tables that support the presented information INDICE: 1. Targeting the Architecture of Deregulated Protein Complexes in Cancer Eduard Stefan 2. Multifaceted nucleolar protein nucleolin and its molecular partners in cancerogenesis Iva Ugrinova Revealing the structural and function impact of mutation in MSH2-MSH6 complex George Priya Doss P. C 4. Proteomics of screening-preventable tumors Nicola Luigi Bragazzi 5. Protein-protein interactions mediated by the N-terminus of neuronal Nitric Oxide Synthase? Jose Ignacio Rodriguez-Crespo? 6. Proteomics of neurological, psychiatric and neurosurgical diseases Nicola Luigi Bragazzi 7. Targeting intramembrane protein-protein interactions: Novel therapeutic strategy of millions years old? Alexander B.? Sigalov 8. Development of therapeutic protein interaction inhibitors? James L. Keck? 9. Homo-and heterodimerization of proteins in cell signaling: inhibition and drug design? Seetharama? D. Jois? 10. Human interactomics: comparative analysis of different interactomes and construction of a protein-drug bipartite network Javier De Las Rivas Sr. 11. Defining HIV-1 replication mechanisms by analyzing virus-host protein interactions Manuel Llano
- ISBN: 978-0-12-814342-1
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 488
- Fecha Publicación: 01/03/2018
- Nº Volúmenes: 1
- Idioma: Inglés