The aim of this volume is to promote further research in the discovery of new therapeutic targets that can be affected by therapeutic proteins and peptides in a desired manner in order to cure or manage symptoms of human diseases. Furthermore, currently well-studied and already established therapeutic proteins/peptides need to be further developed to improve their treatment efficacy and to minimize any adverse effects they might cause. Describes advances in the discovery and application therapeutic proteins/peptides which allow better targeting to the site of treatment and cause fewer adverse effects compared to chemical compounds used for disease treatmentTargeted to a very wide audience of specialists, researchers and studentsChapters are written by well-renown authorities in their fieldThe information provided in the volume is well supported by a number of high quality illustrations, figures and tables INDICE: 1. Rational Design of Stable Liquid Formulations of Biopharmaceuticals Mark Cornell Manning 2. Formulation strategies for peptides, proteins and antibodies using nanotechnology Bruno Sarmento 3. Solution structural dynamics of therapeutic peptides and their adsorption on plasmonic nanoparticles Mahnoud Ghomi 4. Enzymatic approaches of protein-polymer conjugation Gianfranco Pasut 5. Chimeric small antibody fragments as a strategy to deliver therapeutic payloads Joao Goncalves 6. Smart cell-penetrating peptide-based techniques for cytoplasmic delivery of therapeutic macromolecules Yongzhuo Huang 7. Therapeutic protein disaggregases James Shorter 8. In silico tools and databases for designing peptide-based vaccines and drugs Gajendra P.S. Raghava 9. Proteins and peptides for elderly health Jianping Wu 10. Peptide derivatives of Erythropoietin in the treatment of neuroinflammation and neurodegeneration Kursad Genc 11. Antimicrobial peptides structure/function relationship: what can we obtain from structural data? Octavio Luiz Franco 12. Antimicrobial peptides: future antibiotics Viji Sarojini 13. Recent advances in protein and peptide drug delivery systems Jennica L. Zaro
- ISBN: 978-0-12-814340-7
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 488
- Fecha Publicación: 01/05/2018
- Nº Volúmenes: 1
- Idioma: Inglés