Surface and Interface Analysis in Pharmaceutical and Biopharmaceutical Fields

Surface and Interface Analysis in Pharmaceutical and Biopharmaceutical Fields provides a comprehensive review of the most commonly used interface science techniques in drug research and development (including their capabilities and limitations) and relates them to a specific, practical situation. This book outlines sample preparation crucial for a successful outcome and features methods to interpret results that can be combined with other techniques. It provides engineers who work in instrument companies a comprehensive understanding of the specific challenges faced by these techniques in pharmaceutical/biopharmaceutical applications, presenting a framework for new instruments that can be designed to address current challenges. Provides diagrams of drug development roadmapsIncludes snapshots of potential applications of surface and interface characterization at each stage of drug developmentSummarizes major surface/interface characterization techniquesCompares the pros and cons of commonly applied surface/interface characterization techniquesExplores working examples from pharmaceutical and biopharmaceutical fieldsGuides the development of practical strategies for solving real-world problems INDICE: 1. Introduction to small molecule drug product development 2. Introduction to bioproduct development 3. Introduction to packaging and device development 4. Principals of surface and interface characterization techniques 5. Methodology for surface and interface analysis of pharmaceutical and biopharmaceutical samples 6. Applications of surface characterization techniques in drug discovery 7. Applications of surface and interface characterization techniques in small molecule drug product development 8. Applications of surface and interface characterization techniques in bioproduct development 9. Applications of surface and interface characterization techniques in packaging and injectable device development 10. Failure analysis and root cause investigation for manufacturing deviation and complaint samples 11. Current challenges and future trends

• ISBN: 978-0-12-804023-2
• Editorial: Elsevier
• Encuadernacion: Cartoné
• Páginas: 460
• Fecha Publicación: 01/03/2019
• Nº Volúmenes: 1
• Idioma: Inglés