Cardiac bioelectric therapy: mechanisms and practical implications

Pacing and defibrillation have become the leading therapeutic treatments of heart rhythm disorders, including bradycardia and tachycardia. The success of these therapies is largely due to centuries of scientific inquiry into the fundamental mechanisms of bioelectric phenomena in the heart. History of successful development of bioelectric therapies includes development of experimental and theoretical methodologies, novel bioengineering approaches, and state-of-the-art clinical implantable device therapies. The purpose of this book is to present a uniform thematic collection of reviews written by the leading basic andapplied scientists working in basic bioengineering research laboratories, whohave contributed to the development of current understanding of the fundamental mechanisms of pacing and electrophysiology, and who are at the leading edgeof further developments in electrotherapy Over 500 illustrations Historical Overview of Pacing and Defibrillation INDICE: From the contents History of Cardiac Pacing.- History of Defibrillation.- Ventricular Fibrillation: A Historical Perspecitve.- The Bidomain Theory of Pacing.- Bidomain Model of Defibrillation.- The Generalized Activating Function.- Theory of Electroporation.- Critical Points and the ULV for Defibrillation.- The Role of Shock-induced Non-regenerative Depolarization inVentricular Fibrillation and Defibrillation: The Graded Response Hypothesis.- Mechanisms of Isolated Cell Stimulation.- The Role of Microscopic Tissue Structure in Defibrillation.- Virtual Electrode Theory of Pacing.- The Virutal Electrode Hypothesis of Defibrillation.- Simultaneous Optical and Electrical Recordings.- Optical Mapping of Multi-site VF Synchronization.- The Bidomain Model of Cardiac Tissue: From Microscale to Macroscale.-  Multi-electrode Mapping ofthe Heart.- The Role of Electroporation.- Lessons for the Clinical Implant.- Resonance and Feedback Strategies for Low-voltage Defibrillation.

• ISBN: 978-0-387-79402-0
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 725
• Fecha Publicación: 01/11/2008
• Nº Volúmenes: 1
• Idioma: Inglés