Lipid Mediators and Their Metabolism in the Brain presents readers with cutting edge and comprehensive information not only on the synthesis and degradation of glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators, but also their involvement in neurological disorders. It is hoped that this monograph will be useful not only to postgraduate student and their teachers, but also to research scientists and physicians, who are curious about the generation and roles of lipid mediators in the brain. Presents readers with cutting edge and comprehensive information on lipid mediators in a manner that is useful not only to students and teachers, but also to researchers and physicians. Provides a comprehensive description of glycerophospholipid, sphingolipid, and cholesterol-derived mediators, their interactions with each others in normal brain and in brain tissue from neurological disorders. The presentation of this monograph is based on uniformity and logical progression of subject from one topic to another with an extensive bibliography. INDICE: Chapter 1. Metabolism and roles of eicosanoids in brain. Chapter 2. Recent Developments on the neurochemistry of docosanoids. Chapter 3. Metabolism, roles, and involvement of lyso-glycerophospholipids in neurological disorders. Chapter 4. Platelet activating factor in brain: its metabolism, roles and involvement in neurological disorders. Chapter 5. Cannabinoids in the brain:their metabolism, roles, and involvement in neurological disorders. Chapter 6. Neurochemical aspects of 4-hydroxynonenal. Chapter 7. Isoprostanes and othernon-enzymic polyunsaturated fatty acid-derived lipid mediators in the brain. Chapter 8. Ceramide and ceramide 1-phosphate in the brain. Chapter 9. Sphingosine and sphingosine 1 phosphate in brain. Chapter 10. Cholesterol and hydroxycholesterol in the brain. Chapter 11. Perspective and direction for future research on lipid mediators.
- ISBN: 978-1-4419-9939-9
- Editorial: Springer New York
- Encuadernacion: Cartoné
- Páginas: 450
- Fecha Publicación: 29/07/2011
- Nº Volúmenes: 1
- Idioma: Inglés