Microbiota-Brain Axis: A Neuroscience Primer

Microbiota-Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct effective microbiota-brain research, understand the appropriate methodologies, and collect and analyze microbiota data. The book begins with an introduction to the importance of the microbiota-brain communication in development and how microbiota impact neurodevelopmental disorders, mental health and neurodegeneration. In addition, the book discusses advances in microbiota analysis tools and techniques for neuroscience related research. Reviews the many approaches to manipulating the microbiota in animal studies - including the use of germ-free animals, antibiotics and diet - and covers the strengths and limitations of eachOutlines available microbiota research tools, such as 16S sequencing and shot-gun metagenomicsProvides a comprehensive guide to analyzing microbiota-related data and the many choices for bioinformatics INDICE: 1. Gut-brain Axis 2. Research approaches to manipulate/study microbiota 3. Microbiota analysis tools and techniques 4. What is a healthy microbiome? 5. Gene-environment contributions to microbiota composition, diversity, and function 6. Microbiota-brain communication in neurodevelopment - the first 1000 days 7. Microbiota in neurodevelopmental disorders 8. Microbiota-brain interactions in mental health - adolescence and adult 9. Microbiota-brain interactions in neurodegeneration 10. Antibiotics 11. Probiotics 12. Fecal transplantation 13. Microbiota-related biomarkers for precision medicine and drug discovery 14. Future considerations

• ISBN: 978-0-12-814800-6
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 496
• Fecha Publicación: 01/09/2020
• Nº Volúmenes: 1
• Idioma: Inglés