Childhood obesity and its co-morbidities -- including type 2 diabetes, hypertension, dyslipidemia, sleep apnea, and fatty liver disease -- have seen striking increases in recent years. Despite a wealth of investigation, there is considerable controversy regarding the etiology of childhood obesity and the optimal approaches for prevention and treatment. Pediatric Obesity: Etiology, Pathogenesis, and Treatment addresses the controversy with a range of features thatmake it a unique resource for those who care for obese children and their families. Written from a perspective that is international in scope, the distinguished authors re-assess the roles of genetic and environmental factors in the pathogenesis of childhood obesity and critically review new studies of the effects of lifestyle, pharmacologic, and surgical interventions. The evidence-based approach of Pediatric Obesity: Etiology, Pathogenesis, and Treatment provides a comprehensive and invaluable guide for all healthcare providers concernedwith the evaluation and care of children with nutritional and metabolic disease and with the societal implications of the obesity epidemic. Provides an evidence-based, comprehensive guide to the diagnosis and treatment of childhood obesity and its co-morbidities INDICE: Global dynamics in childhood obesity: reflections on a life of work in the field.- The neuroendocrine control of energy balance.- Monogenic obesity.- Syndromic obesity.- Polygenic obesity.- Racial differences in childhood obesity: pathogenesis and complications.- Maternal determinants of childhood obesity: weight gain, smoking, and breast feeding.- Intrauterine growth retardation.- Gestational diabetes.- The roles of diet and energy expenditure in obesity pathogenesis.- The role of diet.- The role of Non-Exercise Activity Thermogenesis (NEAT).- Metabolic complications of childhood obesity.- Childhood obesity and the regulation of growth, thyroid function, sexual development, and calcium homeostasis.- Pathogenesis of insulin resistance and glucose intolerancein childhood obesity.- Pathogenesis and management of dyslipidemia in obese children.- Fatty liver disease.- Pathogenesis of hypertension and renal diseasein obesity.- Sleep-disordered breathing and sleep duration in childhood obesity.- The long-term metabolic complications of childhood obesity.- Childhood obesity, atherogenesis, and adult cardiovascular disease.- Family-based lifestyle and dietary counseling.- Exercise and childhood obesity.- School- and community-based interventions.- Pharmacotherapy of childhood obesity and pre-diabetes.- Pathogenesis and management of adiposity and insulin resistance in the polycystic ovary syndrome.- Obesity and metabolic dysfunction in the child with amajor behavioral disorder: atypical antipsychotics.- Pathogenesis and treatment of hypothalamic obesity.- Bariatric surgery in adolescents.- Neuroendocrineand metabolic adaptations that facilitate weight re-gain.- The socio-culturalcontext for obesity prevention and treatment in children and adolescents: influences of ethnicity and gender.- The marketing and distribution of fast food.- Local and national policy-based interventions.- Appendix.
- ISBN: 978-1-60327-873-7
- Editorial: Humana
- Encuadernacion: Cartoné
- Páginas: 516
- Fecha Publicación: 29/08/2010
- Nº Volúmenes: 1
- Idioma: Inglés