Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part II builds on the foundation from Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phakomatoses. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist. Comprehensive coverage of neurogeneticsDetails the latest science and impact on our understanding of neurological psychiatric disordersA focused reference for clinical practitioners and the neuroscience/neurogenetics research community INDICE: Section V. Dementias 26. The genetic landscape of Alzheimer disease 27. Frontotemporal dementia 28. The genetics of dementia with Lewy bodies 29. Prion disease Section VI. Paroxysmal Disorders 30. Genetics of epilepsy 31. Genetics of migraine 32. Periodic paralysis 33. Episodic ataxias 34. Disorders of sleep and circadian rhythms Section VII. Neuromuscular Disorders 35. Facioscapulohumeral muscular dystrophy 36. The genetics of congenital myopathies 37. Genetic basis and phenotypic features of congenital myasthenic syndromes 38. Spinal muscular atrophy 39. Emerging understanding of the genotype: Phenotype relationship in amyotrophic lateral sclerosis 40. Spinal and bulbar muscular atrophy 41. Hereditary spastic paraplegia 42. Neuropathy Section VIII. Diseases of White Matter and Demyelination 43. The spectrum of adult-onset heritable white matter disorders 44. Alexander disease 45. Neurogenetics of Pelizaeus-Merzbacher disease 46. Multiple sclerosis Section IX. Cerebrovascular Diseases 47. CADASIL Section X. Major Adult Psychiatric Disorders 48. Neuroepigenetics and addiction 49. Genetic susceptibility in obsessive-compulsive disorder Section XI. Cancer and Phakomatoses 50. Brain cancer genomics and epigenomics 51. Neurofibromatosis type 1 52. Tuberous sclerosis complex 53. Von Hippel-Lindau disease and Sturge-Weber syndrome
- ISBN: 978-0-444-64076-5
- Editorial: Elsevier
- Encuadernacion: Cartoné
- Páginas: 340
- Fecha Publicación: 05/01/2018
- Nº Volúmenes: 1
- Idioma: Inglés