Forkhead FOXO Transcription Factors in Development and Disease, Volume 127, the latest release in the Current Topics in Developmental Biology series provides a comprehensive set of reviews on transcription factors FOXO and their various functions in health and disease. Each chapter is contributed by a leading expert in the field, with specific sections covering Exceptional Longevity: Insights from Hydra to Humans, FOXO in neural cells and diseases of the nervous system, maintaining the equilibrium for better or for worse, and The Role of FoxOs in Bone Health and Disease, amongst other topics. This compilation provides a unique, up-to-date view of this enigmatic, highly evolutionary conserved family of transcription factors with a diverse array of functions in aging and longevity, cancer, and metabolism. Provides the authority and expertise of leading contributorsIncludes sections on the regulation of FOXO factors and stem cellsPresents a unique view of this highly evolutionary family of transcription factors INDICE: 1. FOXO3 and Exceptional Longevity: Insights from Hydra to Humans Bradley John Willcox 2. FOXO in neural cells and diseases of the nervous system JI-HYE PAIK 3. FOXOs maintaining the equilibrium for better or for worse Boudewijn Burgering 4. The Role of FoxOs in Bone Health and Disease Maria Almeida 5. FoxO Transcription Factors and Diabetes: Integrated Effects on Lipid and Glucose Metabolism Promotes the Adaptation to Fasting and Diabetes Terry Unterman 6. C. elegans FOXO/DAF-16: lifespan, metabolism and more Heidi Tissenbaum 7. Regulation of FOXO factors Ashley Webb 8. FOXO and Stem cells Saghi Ghaffari
- ISBN: 978-0-12-804253-3
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 536
- Fecha Publicación: 01/02/2018
- Nº Volúmenes: 1
- Idioma: Inglés