Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges

Traditionally, tablets, capsules, syrups solutions and ointments were the most popular dosage forms for delivering drugs to patients for different ailments. However, in recent years the introduction of a number of different and novel dosage forms have started shifting the traditional paradigm of dosage forms. So called 'novel drug delivery systems' are numerous, and each have different approaches of their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are some of the aspects which researchers should know before start working on these carriers. Currently, individual literature is available at discrete levels for each of these novel drug carriers such as vesicular carriers, nanoparticles, dendrimers, but there is no comprehensive title that includes the basics of biotherapeutics delivery for protein/hormone based carriers, aspects of gene delivery, monoclonal antibodies, vaccine and sera, aptamers and antisense oligonucleotides. Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource to readers from the beginner to an established scientist with a fundamental knowledge with the key challenges of these carriers at molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand the crucial aspects such as regulatory, clinical, toxicological and formulation requirement of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery. Conceptual understanding of Molecular Pharmaceutics and drug/gene delivery systems of biological origin A detailed description and discussion on the nanotechnological carriers from basics to advances including gene delivery and protein-oriented delivery Regulatory as well as toxicological requirements of the novel drug delivery systems INDICE: 1. Molecular Pharmaceutics: An Introduction 2. Protein and Enzymes Based Formulations 3. Current and Advanced Approaches in Gene Therapy4. Vaccine and Sera 5. Aptamers and Antisense Oligonucleotides Based Delivery6. Monoclonal Antibodies7. Hormonal Delivery Systems8. Vesicular Drug Delivery Systems 9. Polymeric Micelles Vs Micelles in Drug Delivery and Targeting10. Nanoparticulate Drug Delivery Systems11. Inorganic and Metal based Nanoparticles12. Dendrimers: Promises and Challenges in Drug Delivery13. Advances in Diagnostics14. Fundamentals of Targeted Drug Delivery Systems15. Toxicological, Clinical and Regulatory Aspects of Novel Drug Delivery Systems: Recent Updates

• ISBN: 978-0-323-91924-1
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 350
• Fecha Publicación: 01/11/2022
• Nº Volúmenes: 1
• Idioma: Inglés