This volume focuses on the mechanisms of cell injury and cell survival in thebrain, with special emphasis on development and early life, in relation to hypoxia and ischemia in the brain. The major reason for the emphasis placed on the developmental stages of the brain is the major societal and economic burdenof the affliction when it occurs in early life Most up-to-date volume to focus on the mechanisms of cell injury and cell survival in the brain, with special emphasis on development and early life, in relation to hypoxia and ischemia in the brain Comments on the developmental stages of the brain is the major societal and economic burden of the affliction when it occurs in early life INDICE: Hybernation and CNS survival.- High CO2 and ischemia.- ROS and brain injury in ischemia.- Apoptotic surface delivery of K+ channels.- Intermittent low O2 and brain function.- Mechainsms of injury and survival in hypoxia and ischemia in the CNS.- Regulation of apoptotic volume decrease and apoptosis by plasma membrane aquaporin activity.- Mitochondrial mechanisms in ischemia/hypoxia.- Blood flow and hypoxia/ischemia in CNS.- Mitochondrial permeability transition and cell death.- Neurodegeneration and hypoxia/ischemia.- Glutamate and NO in the CNS.- HIF and brain hypoxia.- Calcium-permeable acid-sensing ionchannels in brain ischemia.- Regulation of ion channels and receptors in brain ischemia.- Factors influencing cell death in the penumbra.- Critical roles of Na+,K+-ATPase in apoptosis and CNS diseases.- Mechanisms of tolerance/susceptibility in the CNS.- SIDS and PVL/prematurity and white matter injury.
- ISBN: 978-1-60327-578-1
- Editorial: Humana
- Encuadernacion: Cartoné
- Páginas: 265
- Fecha Publicación: 01/01/2009
- Nº Volúmenes: 1
- Idioma: Inglés