Feedback Control for Personalized Medicine provides ideas on ongoing efforts and obstacles by members of the control engineering community in different biological and medical applications. In addition, the book presents key challenges, insights, tools and theoretical developments that arise from personalized medicine, along with medical concepts that are explained by engineers to help non-experts follow research topics. Several clinical trials have tried to find therapeutic approaches to achieve eradication or at least lifelong, therapy-free, host control of the infection. This has been performed integrating clinical observations, empirical knowledge and information from medical tests to treat patients. As this trial and error? approach is becoming more challenging and unfeasible by the steep increase in the number of different pieces of information and the complexity of large datasets, a systematic and tractable approach that integrates a variety of biological and medical research data into mathematical models and computational algorithms is crucial to harness knowledge and to develop new therapies towards personalized medicine. Presents the most recent research in personalized medicine using control theoretical tools Offers numerical simulations that are analyzed in detail and compared with control experiments Brings the most recent research of control theory in medicine INDICE: 1. Introduction to Control Theory Towards Personalized Medicine2. Control schemes for Personalizing Therapies3. Input-output approaches for personalized drug dosing of antibiotics4. Safe glycemia regulation considering parameter variations under the offset-free MPC with pulse inputs scheme5. Glycemia regulation using Neural Networks6. Personalizing therapeutic treatments in Influenza Infection7. Polynomial state estimation in infectious diseases8. Sliding mode control theory interprets elite control of HIV9. A stochastic model for Hepatitis C viral infection dynamics with the innate immune response10. First approach to impulsive nonlinear MPC with application to Oncolytic Virus Therapy11. Is the isolated heart a relaxation oscillator?
- ISBN: 978-0-323-90171-0
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 220
- Fecha Publicación: 01/05/2022
- Nº Volúmenes: 1
- Idioma: Inglés