Synthesis and Applications of Isotopically-Labelled Compounds: Recent Advances and Emerging Topics

Synthesis and Applications of Isotopically-Labelled Compounds: Recent Advances and Emerging Topics reviews recent advances in the field of tritium, carbon-14, and stable isotope compound synthesis along with their analysis. The emerging field of the development of deuterated pharmaceuticals is also discussed, along with the application of isotopically labelled compounds in drug metabolism studies. There book presents a comprehensive guide to the field for the community, as well as newcomers, interested parties, or collaborators who need to be able to communicate with labeling groups. This book fills this gap and provides a one-stop shop by having a comprehensive review of recent developments. Sections cover analytical chemistry in depth and include new sections on methods of stable isotope analysis. Analytical chemistry aspects of these specific areas are also covered. Provides a complete review of the synthesis of isotopically labelled compounds in a single volumeReviews the emerging field of deuterated pharmaceuticals as therapeuticsCovers recent advances in the field of tritium, carbon-14, and stable isotope compound synthesis INDICE: 1. General Introduction2. Recent advances in tritium chemistry3. Recent advances in carbon-14 chemistry4. Recent advances in the chemistry of PET and SPECT isotopes5. Recent advances in the chemistry of stable isotopes6. Preclinical and clinical studies of pharmaceuticals supported by labelled compounds7. Non pharmaceutical applications of labelled compounds8. Emerging new fields in the chemistry of isotopes and their application9. Deuterated APIs10. Recent advances in the analysis of isotopically labelled compounds11. Radiolabeling of large molecules12. Summary and outlook

• ISBN: 978-0-443-19154-1
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 250
• Fecha Publicación: 01/09/2025
• Nº Volúmenes: 1
• Idioma: Inglés