Non-Viral Vectors for Gene Therapy: Nonviral Vector-Mediated Gene Transfer

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Includes methods for testing with ethical, legal, and social implicationsCritically analyzes future directionsWritten and edited by recognized leaders in the field INDICE: Historical account of the field, and major barriers that prevent the delivery of genetic materials to the target cells and intracellular compartmentsLeaf HuangProlonged expression of cDNA Richard Paul HarbottleNon-coding RNA John J RossiOverview Leaf HuangIonizable lipids and LNPsPieter R. Cullis Lipidoids Daniel G. AndersonOverview Ernst Wagner Mucosal delivery of RNAi therapeuticsKenneth A. HowardRecent developments in nucleic acid delivery with Polyethylenimines and its derivativesAntoine KichlerBioresponsive block copolymersKazunori Kataoka Overview Leaf HuangMultifunctional Enveloe-type Nano Device for gene delivery: Concept and Application to NanomedecineHideyoshi Harashima       Lipid coated calcium phosphate nanoparticlesLeaf HuangOverviewDexi Liu Ultrasound Kazuo MaruyamaElectroporationDavid A. Dean Hydrodynamic injectionDexi LiuReinventing the gene vaccine:  Non-viral delivery of conventional and self-amplifying mRNAAndrew J. Geall Toxicity concerns of non-viral gene deliveryS. Moein Moghimi Clinical trial of non-viral gene therapyRichard Heller

• ISBN: 978-0-12-800148-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 120
• Fecha Publicación: 12/11/2014
• Nº Volúmenes: 1
• Idioma: Inglés