Suppressing the mind: anesthetic modulation of memory and consciousness

This book will present original results as well opinionated overviews of the current state of knowledge of the problem of anesthesia-induced unconsciousness and amnesia. It will present evidence from molecular to system levels and lead to an integrative theory of anesthetic-induced unconsciousness and amnesia.The hypothesized mechanism underlying anesthetic action will be explored as ademonstration of 'bridging the gap' between bench and clinical research. It will synthesize information spanning a number of levels from molecular integrative that has begun to reveal answers to the longstanding mystery of anesthesia. Multidisciplinary collection of original results and authoritative overviewsof the current state of knowledge Written by investigators internationally known for their significant contribution to the current understanding of the mechanism of anesthesia Bridges molecular, cellular, integrative and systems-level actions of anesthetics with respect to their effects on consciousness and memory INDICE: Introduction.- Molecular targets of general anesthetics in the nervous system.- A neurochemical perspective on states of consciousness.- Anesthetic modulation of auditory perception: linking cellular, circuit and behavioral effects.- Cortical disintegration mechanism of anesthetic-induced unconsciousness.- Anesthesia and the thalamocortical system.- Anesthesia-induced state transitions in neuronal populations.- Anesthesia awareness: when the mind is not suppressed.- Loss of recall and the hippocampal circuit effects produced by anesthetics.- Modulation of the hippocampal theta rhythm as a mechanism for anesthetic-induced amnesia.- Propofol amnesia – what is going on in the brain?

• ISBN: 978-1-60761-463-0
• Editorial: Humana
• Encuadernacion: Cartoné
• Páginas: 350
• Fecha Publicación: 01/12/2009
• Nº Volúmenes: 1
• Idioma: Inglés