The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virusparticle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general. The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoesprogrammed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides INDICE: Preface.- Flock House Virus: A Model System for Understanding Non-enveloped Virus Entry and Membrane Penetration.- The Caliciviruses.- Picornaviruses.- From Touchdown to Transcription: The Reovirus Cell Entry Pathway.- Rotavirus Cell Entry.- Structures and Functions of Parvovirus Capsids and the Process of Cell Infection.- Cellular Entry of Polyomaviruses.- Adenovirus.- Subject Index.
- ISBN: 978-3-642-13331-2
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 240
- Fecha Publicación: 15/06/2010
- Nº Volúmenes: 1
- Idioma: Inglés