This volume in the International Review of Neurobiology is a comprehensive overview of the state-of-the-art research into autism pathophysiology. Its chapters cover a wide range of etiologies, from genetics and development to environmental factors. In addition, it discusses key cell and behavioral phenotypes, including cortical and cerebellar phenotypes, as well as language and motor outputs. Finally, this volume's chapters on gene expression in the brain describe how genes may be connected to phenotypes in autism. Broad coverage of genetic and cellular phenotypes in autismFocused on basic research Chapters primarily written by new investigators with a fresh perspective on the biological underpinnings of autism INDICE: Autism Spectrum Disorder and the Cerebellum Esther B. E. Becker and Catherine J. Stoodley Contribution of Long Noncoding RNAs (lncRNAs) to Autism Spectrum Disorder Risk Brent Wilkinson and Daniel B. Campbell Identifying Essential Cell Types and Circuits in Autism Spectrum Disorders Susan E. Maloney, Michael A. Rieger, and Joseph D. Dougherty Connecting Signaling Pathways Underlying Communication to ASD Vulnerability Stephanie Lepp, Ashley Anderson, and Genevieve Konopka MET Receptor Tyrosine Kinase as an Autism Genetic Risk Factor Yun Peng, Matt Huentleman, Christopher Smith, and Shenfeng Qiu Transcriptional Dysregulation of Neocortical Circuit Assembly in ASD Kenneth Y. Kwan Motor Skill in Autism Spectrum Disorders: A Subcortical View Leanne Chukoskie, Jeanne Townsend, and Marissa Westerfield Orchestration of Neurodevelopmental Programs by RBFOX1: Implications for Autism Spectrum Disorder Brent R. Bill, Jennifer K. Lowe, Christina T. DyBuncio and Brent L. Fogel Immune Dysregulation in Autism Spectrum Disorder Elaine Y. Hsiao Autism Susceptibility Genes and the Transcriptional Landscape of the Human Brain Shingo Miyauchi and Irina Voineagu
- ISBN: 978-0-12-418700-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 384
- Fecha Publicación: 13/12/2013
- Nº Volúmenes: 1
- Idioma: Inglés