Anticandidal Therapeutics: Discovery and Development helps researchers form the basis of discovery and development of novel anticandidal therapies. In 14 chapters, the book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical study status of anticandidal therapeutic agents, and drug repurposing for the development of novel anticandidals. This book provides readers with comprehensive knowledge on the fungal human infection candida and the development of anticandidal drugs. Developments of anti-fungal agents have declined as compared to other antibiotics. There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida. Highlights the mechanics of actions of all therapeutic agents against Candida Focuses on anticandidal agents rather than general antifungal agents Discusses the stage of development of new antifungal drugs, the reposition of drugs, and how this could help in treatment INDICE: 1. Introduction 2. Basic biology of fungal pathogen Candida 3. Fungal pathogen Candida diseases 4. Candidiasis and immune-compromised patients 5. Anticandidal Agents 6. Anticandidal Diet 7. Multidrug transporters of fungal pathogen Candida 8. Essential anticandidal targets 9. Stages of anticandidal agents development 10. Recent trends and progress in antifungal translational research 11. Clinical studies status of anticandidal therapeutic agents 12. Drug repurposing for development of effective anticandidals 13. Challenges and future prospect 14. References
- ISBN: 978-0-443-18744-5
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 266
- Fecha Publicación: 01/01/2023
- Nº Volúmenes: 1
- Idioma: Inglés
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