From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors
Langmead, Christopher J.
From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo-switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP-1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure-based discovery and development of mGlu5 NAMs, and much more. Includes the authority and expertise of leading contributors in pharmacologyPresents the latest release in the Advances in Pharmacology series INDICE: 1. Targeting muscarinic M1 receptor in neurodegenration Sophie Bradley 2. Photo-switchable allosteric ligands Cyril Goudet 3. Computational approaches for the design of mGlu receptor allosteric modulators Gary Tresadern 4. Allosteric modulation of GLP-1 receptor in metabolic disorders Francis Willard 5. Group II mGluR roles in the nervous system and their roles in addiction David Lovinger 6. RAMPs as allosteric modulators of Class B GPCRs Augen A. Pioszak 7. Structure-based discovery and development of mGlu5 NAMs Kirstie Bennett 8. Allosteric modulation of taste receptors Guy Servant 9. Structure-based identification of adenosine A1 receptor allosteric modulators Lauren Therese May 10. Allosteric modulation of muscarinic receptors in addiction Andrew J. Lawrence 11. Mechanisms of allosteric modulation of GABAB receptors Julie Kniazeff
- ISBN: 978-0-12-820187-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 312
- Fecha Publicación: 01/06/2020
- Nº Volúmenes: 1
- Idioma: Inglés