Imaging Neuroinflammation provides an overview of the influence of inflammation on neuroanatomy, what imaging tools are available to probe neuroinflammation in the brain and spinal cord, and the application of those tools to preclinical models and human imaging. This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, Adaptive Optics (OCT) of inflammation, and more. Explains how inflammation in the central nervous system impacts tissue microstructure Presents imaging methods that are useful for assessing neuroinflammation Describes preclinical models of neuroinflammation Summarizes the role of neuroinflammation in several human injury and disease states INDICE: 1. Prologue 2. Molecular and tissue basis of inflammation Biochemical factors of inflammation, explain cellular/tissue responses Imaging Approaches to Inflammation 3. Gadolinium of BBB imaging Including vessels 4. Gadolinium Leptomeningeal imaging Including vessels 5. USPIO / magnetic particle imaging 6. CEST 7. PET Technical, not focused on applications 8. Adaptive Optics OCT ie https://www.pnas.org/content/117/48/30661 Animal Models 9. Animal models of inflammation neuro model (EAE, Herpes?) and body model (viral hepatitis? Lupus/RA) Human inflammation-based diseases 10. MS Include spinal cord inflammation, NMO 11. Pediatric Leukodystrophies Inflammatory ones 12. Infections/encephalitis (viral: HIV, Covid, bacterial, misc ) 13. Lupus 14. Dementia (Alzheimer's, include viral theory) 15. Vasculitis Vessel wall imaging
- ISBN: 978-0-323-91771-1
- Editorial: Academic Press
- Encuadernacion: Rústica
- Fecha Publicación: 05/01/2023
- Nº Volúmenes: 1
- Idioma: Inglés