Since 1970, Current Topics in Membranes has sought to provide outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. The serial is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. Researchers are encouraged to fully explore their ideas that are often limited in normal scientific publication formats due to strict space constraints. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes Contains original material, both textual and illustrative, that make it a very relevant referencePresented in a very comprehensive mannerBoth researchers in the field and general readers will find this book relevant and up-to-date with regard to its information INDICE: Membrane structure and general mechanisms of sterol regulation of ion channels 1. Regulation of ion channels by sterols as boundary lipids 2. Differential effects of sterols on ion channels: specific vs. non-specific interactions Structural determinants of cholesterol-ion channels interactions 3. Regulation of Ca2+-sensitive K+ channels by cholesterol and bile acids via distinct channel subunits and sites 4. The role of cholesterol in activation and coupling of nicotinic acetylcholine receptors 5. Multiple mechanisms of regulation of Transient Receptor Potential ion channels by cholesterol 6. Direct interactions of cholesterol with pentameric ligand-gated ion channels: Testable hypotheses from computational predictions 7. Identification of novel cholesterol binding regions distinct from known cholesterol binding motifs in Kir channels Emerging topics of cholesterol regulation of ion channels 8. Regulation of P2X purinergic receptor signaling by cholesterol 9. Modulation of the Drosophila TRPL channel activity by cholesterol 10. Sterol regulation of voltage-gated K+ channels
- ISBN: 978-0-12-809388-7
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Fecha Publicación: 01/11/2017
- Nº Volúmenes: 1
- Idioma: Inglés