The Handbook of Metabolic Phenotyping

The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores the wide array of analytical chemistry and statistical modelling techniques used in the field, also presenting surveys of various application areas in human development, nutrition, disease, therapy and epidemiology. The book covers recent studies that integrate the various -omics datasets to derive a system biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts, the book is a valuable resource for post-grads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotypingExplores, in detail, the many diverse statistical approaches used in the fieldOffers practical tips for successfully conducting metabolic phenotyping studiesFeatures reviews of all of the various fields of activity relating to human studies INDICE: 1. The role of metabolic phenotyping in modern medicine2. NMR spectroscopy methods3. LC-MS methods4. GC-MS methods5. CE-MS methods 6. MS imaging and i-knife methods7. Univariate statistics methods8. Multivariate statistics methods9. Data visualisation approaches10. Big data and databases11. Standardisation of methods12. Phenome centres13. Plant sciences14. Microbial and invertebrate applications15. Applications to pharmaceuticals16. Application to nutrition17. Clinical diagnosis and prognosis metabolic phenotyping18. Metabolic phenotyping in epidemiology19. Gut microflora studies20. Omics integration studies21. Concluding remarks and the future

• ISBN: 978-0-12-812293-8
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 572
• Fecha Publicación: 01/09/2018
• Nº Volúmenes: 1
• Idioma: Inglés