Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients. INDICE: 1 Immunology primer2 Mechanisms of alloimmunization to RBC antigens and testing methodologies 3 Autoimmunity: cold and warm autoantibodies, and autoimmune hemolytic anemia4 Allergic immune reactions to blood components 5 Changing landscape in transfusion-transmitted infections6 Transfusion-related immunomodulation7 Transfusion-related acute lung injury8 HLA-alloimmunization, platelet refractoriness, and post-transfusion purpura 9 Alloimmunization in pregnancy10 Fetal and neonatal alloimmune thrombocytopenia, and neonatal neutropenia 11 Alloimmunization in chronically-transfused patients and those with malignancies 12 Graft-versus-Host disease and Transfusion-associated Graft-versus-Host disease 13 Complications of ABO- and non-ABO-incompatible stem cell transplantations 14 Complications of haploidentical and mismatched HSC transplantation15 Apheresis therapy in immunological disorders and its immune complications16 Passive monoclonal and polyclonal antibody therapies17 Chimeric antigen receptor therapies
- ISBN: 978-0-323-67509-3
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 380
- Fecha Publicación: 27/08/2019
- Nº Volúmenes: 1
- Idioma: Inglés