Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patientsProvides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure INDICE: 1. Introduction 2. Distinction between sex and gender CELLULAR AND TISSUE ELECTROPHYSIOLOGY 3. Sex differences in cardiac ion channels 4. Atrial and ventricular electrophysiology 5. Cardiac conduction system 6. Cellular effects of sex hormones ELECTROCARDIOGRAPHY 7. Normal resting electrocardiogram 8. QRS duration 9. QT interval and QT/RR relationship 10. T wave morphology and ventricular gradient 11. QT variability 12. T wave alternans 13. Electrocardiographic changes during menstrual cycle 14. Development of electrocardiographic sex differences during puberty CARDIAC AUTONOMIC REGULATION 15. Baseline characteristics 16. Cardiac autonomic responses to provocative stimuli 17. Circadian pattern of cardiac autonomic status 18. Sex differences in age influence 19. Autonomic changes during menstrual cycle CHANNELOPATHIES 20. Congenital long QT syndrome 21. Congenital short QT syndrome 22. Brugada syndrome DRUG-INDUCED ELECTROPHYSIOLOGY ABNORMALITIES 23. Mechanisms drug-induced QT interval prolongation 24. Mechanisms of Torsade de Pointes tachycardia CARDIOMYOPATHIES 25. Arrhythmogenic right ventricular cardiomyopathy 26. Hypertrophic cardiomyopathy 27. Dilated cardiomyopathy SUPRAVENTRICULAR TACHYCARDIAS 28. Supraventricular ectopies 29. Focal supraventricular tachycardia 30. Atrioventricular nodal reentrant tachycardia 31. Accessory pathway and atrio-ventricular reentrant tachycardia 32. Ablation of nodal and atrio-ventricular accessory pathways 33 Paroxysmal supraventricular tachycardia during menstrual cycle 34 Supraventricular tachycardias during pregnancy ATRIAL FIBRILLATION 35. Incidence and sex differences in AF progression 36. Atrial fibrillation comorbidities 37. Cardioversion 38. Access to catheter ablation of atrial fibrillation 39. Demographics and procedural data differences of AF ablation 40. Complications of atrial fibrillation ablation 41. Anticoagulation therapy 42. Stroke risk and incidence 43. Rhythm control for atrial fibrillation 44. Quality of life with permanent AF MYOCARDIAL ISCHEMIA AND INFARCTION 45. Incidence and sex differences in IHD progression 46. Electrocardiographic manifestation 47. Acute MI and cardiogenic shock 48. Arrhythmias of acute and subacute phase of MI 49. Sex-specific outcome of post-MI follow-up 50. Sex differences in ICU alarms VENTRICULAR TACHYCARDIAS 51. Ventricular arrhythmias associated with structural heart disease 52. Catheter ablation of ventricular arrhythmias associated with structural heart disease 53. Idiopathic ventricular arrhythmias 54. Catheter ablation of idiopathic ventricular arrhythmias 55. Outcome of ventricular catheter ablation 56. Treatment and handling of Torsade de Pointes tachycardia 57. Ventricular tachyarrhythmia during pregnancy 58. Pregnancy in congenital long QT syndrome SUDDEN CARDIAC DEATH 59. Demographics and epidemiology 60. Cardiac risk in the young 61. Sex-specific mechanisms of sudden cardiac death 62. Sex-specific risk assessment 63. Relationship to athletic training DRUG THERAPY 64. Safety and efficacy of antiarrhythmic drugs 65. Dose responses 66. Clinical implications of acquired LQTS during pregnancy and menopause 67. Antiarrhythmic drug therapy during pregnancy and menopause DEVICE BASED THERAPIES 68. Clinical outcomes of antibradycardia pacing 69. Sex-specific complications of antibradycardia pacing 70. Utility of Implantable cardioverter-defibrillators 71. ICD registries and sex-specific metanalyses 72. Primary and secondary prevention of SCD in women 73. Sex-specific selection of patients benefitting from cardiac resynchronisation therapy 74. Use of CRT in women 75. Trials of cardiac resynchronization therapy 76. CRT registries and sex-specific metanalyses 77. Lead extraction OUTLOOK 78 Obstacles for enrolment of women in clinical trials 79 Policies by scientific societies 80 Regulatory implications

• ISBN: 978-0-12-817728-0
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 750
• Fecha Publicación: 01/06/2020
• Nº Volúmenes: 1
• Idioma: Inglés