Nuclear medicine radiation dosimetry: advanced theoretical principles

Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grownover the past decade. This is due primarily to four factors: Growing consideration of accurate patient-specific treatment planning for radionuclide therapyas a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport anddosimetry in patients, Design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and dosimetry which requirethe user to have a thorough understanding of the theoretical principles used in such algorithms, their appropriateness and their limitations, increasing regulatory scrutiny of the radiation dose burden borne by nuclear medicine patients in the clinic and in the development of new radiopharmaceuticals, thus requiring more accurate and robust dosimetry evaluations. An element common to all four factors is the need for precise radiation dosimetry in nuclear medicine, which is fundamental to the therapeutic success of a patient undergoing radionuclide therapy and to the safety of the patients undergoing diagnostic nuclear medicine and PET procedures. As the complexity of internal radiation dosimetry applied to diagnostic and therapeutic nuclear medicine increases, this book will provide the theoretical foundations for: enabling the practising nuclear medicine physicist to understand the dosimetry calculations being used and their limitations, allowing the research nuclear medicine physicist to critically examine the internal radiation dosimetry algorithms available and under development; and providing the developers of Monte Carlo codes for the transport of radiation resulting from internal radioactive sources with the only comprehensive and definitive." INDICE: The Role of Radiation Dosimetry in Nuclear Medicine.- Theoretical Tools.- Nuclear Properties, Structure and Stability.- Radioactive Decay: Microscopic Theory.- Radioactive Decay: Macroscopic Theory.- Photon Interactions with Matter.- Charged Particle Interactions with Matter.- Radiation Fields and Radiometrics.- Radiation Dosimetry: Theory, Detection and Measurement.- Biological Effects of Ionising Radiation.- Nuclear Medicine Dosimetry.- Anthropomorphic Phantoms and Models of Biological Systems.- The Biodistribution (I) Preclinical.- The Biodistribution (II)- Human.- The Biodistribution (III)- Analysis.-The Ethics of Using Human Subjects.- The Future of Nuclear Medicine Dosimetry.

• ISBN: 978-1-84882-125-5
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 464
• Fecha Publicación: 01/06/2010
• Nº Volúmenes: 1
• Idioma: Inglés