Lactic Acid Bacteria as Cell Factories: Synthetic Biology and Metabolic Engineering

Lactic Acid Bacteria as Cell Factories: Synthetic Biology and Metabolic Engineering describes the most recent developments on the metabolic engineering and synthetic biology of Lactic Acid Bacteria (LAB) for production of biologically active biomolecules (enzymes, organic acids, bacteriocins, bioactive peptides, etc.), recombinant proteins, and their role in bioremediation. The book focuses on synthetic biology and metabolic engineering for the production of biologically active molecules such as bioactive peptides, polysaccharides, vitamins (Riboflavin), enzymes, organic acids (lactic and gamma-aminobutyric acid), flavor and aroma compounds, bacteriocins, recombinant proteins, etc. Individual chapters are devoted to the production of biosurfactants and their applications and the bioremediation of heavy metals by LAB from aquatic environments. Two critical chapters address Genome editing of LAB: opportunities for food, feed and pharmaceuticals and A synthetic biology approach for plasmid DNA and Recombinant protein production. This book will be a valuable resource for those working in biology, biotechnology, biological engineering, chemical engineering, microbiology, food science and technology, genetics and synthetic biology. Explores the synthetic biology and metabolic engineering of lactic acid bacteria Highlights LAB enzymes such as phytase and amylase applications in food processing and the removal of anti-nutrients from foods and lignocellulose bioconversion Presents insights into biosurfactant production and possible applications Includes information on bioremediation by LAB, biofilm production mechanism, and plasmid and recombinant protein production using synthetic biology INDICE: 1. Synthetic biology and metabolic engineering for improvement of LAB as cell factories2. Lactic acid microbial production and recovery: review and recent advances in processes integration3. Lactic acid bacteria for riboflavin production4. Lactic acid bacterial cell factories for production of gamma-aminobutyric acid5. Exopolysaccharides from LAB: Perspectives and challenges6. Lactic acid bacteria for the generation of bioactive peptides7. LAB as a potential source of enzymes: genes to industrial applications8. Amylolytic lactic acid bacteria: Cell factories for direct lactic acid production from biomass by simultaneous saccharification and fermentation9. Cell factories for micronutrient bioavailability of phytate rich foods by phytase producing lactic acid bacteria 10. Production of flavor compounds by LAB in fermented foods 11. Biotechnology of bacteriocins production by LAB12. Biosurfactants production by LAB and emerging applications within bioeconomy13. Synthetic biology approaches towards biosurfactants production14. LAB as cell factory for bioconversion of lignocellulosic biomass15. LAB in biorefinery16. LAB as green biorefinery17. Lactic acid bacteria as biocontrol agents of pathogens18. The reducing power of LAB in fermentations and biomass production19. Bioremediation of heavy metals from aquatic environment by LAB20. LAB as cell factories: A synthetic biology approach for plasmid DNA and recombinant protein production21. Genome editing of LAB: Opportunities for food, feed and pharmaceuticals

• ISBN: 978-0-323-91930-2
• Editorial: Woodhead Publishing
• Encuadernacion: Rústica
• Páginas: 350
• Fecha Publicación: 01/03/2023
• Nº Volúmenes: 1
• Idioma: Inglés