Long Range Regulation of V(D)J Recombination, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes. Focuses on the generation of an effective immune response to invading pathogens Contains contributions from leading authoritiesInforms and updates on all the latest developments in the field of immunology INDICE: Molecular Mechanisms that Underpin the Assembly of Antigen Receptor Variable Region ExonsMeinrad BusslingerLong-range genomic interactions in the TCRb locusEugene OltzRAG1 and RAG2: VDJ recombination and beyondDavid SchatzLong-range genomic interaction in the TCRa locusMichael KrangelIgh Locus topologyRanan SenAllelic exclusion in the TCRb locusPierre FerrierAntigen receptor topologyJane A. SkokLong-range DNA interactions in the Ig kappa locus in the mouseRudi Hendriks
- ISBN: 978-0-12-803296-1
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 198
- Fecha Publicación: 01/11/2015
- Nº Volúmenes: 1
- Idioma: Inglés