Endogenous toxins: targets for disease treatment and prevention

Designed as a first-stop reference for researchers and professionals in toxicology, pharmacology and medicine, this handbook presents the complete picture on what is currently known about endogenous toxins, including their generation, mode of action, resulting disease condition, and available countermeasures. The first of four parts systematically covers important toxic molecule species, including metabolic intermediates and reactive oxygen species. The second part discusses the role of genetically determined metabolic malfunctions, such as galactosemia, hyperlipidemia, porphyria, hemochromatosis and related conditions. Part three discusses acquired and chronic diseases caused or exacerbated by endogenous toxins, such as hepatic injury, asthma, rheumatism, colorectal cancer, reperfusion diseases, neurodegneration and aging. The final part reviews currents stategies to control and minimize the effect of endogenous toxins, either by nutritional or pharmacological interventions.

• ISBN: 978-3-527-32363-0
• Editorial: Wiley-VCH
• Encuadernacion: Cartoné
• Páginas: 982
• Fecha Publicación: 21/10/2009
• Nº Volúmenes: 1
• Idioma: Inglés