Social Aspects of Drug Discovery, Development and Commercialization

Social Aspects of Drug Discovery, Development and Commercialization provides an insightful analysis of the drug discovery and development landscape as it relates to society. This book examines the scientific, legal, philosophical, economic, political, ethical and cultural factors that contribute to drug development. The pharmaceutical industry is under scrutiny to develop safer and more effective drugs in a quicker and more affordable manner. Recent criticism and debates have emphasized varying opinions on the issues concerning the drug discovery and development process. This book provides thoughtful and valuable discussions and analysis of the social challenges and potential opportunities through all stages of the pharmaceutical process, from inception through marketing. With a unique focus on the social factors that increasingly play a role in how drug development is planned, structured, and executed throughout the drug product lifecycle, this is an essential resource for students, professors, and researchers who seek a better understanding of the interface between the pharmaceutical industry, health care systems, and society. Organized in a sequence of interrelated theories and principles that provide the foundation for increased understanding of the relevant social aspectsIncludes analysis of important new advances, key scientific and strategic issues, and overviews of recent progress in drug developmentProvides a global perspective with examples from developed areas, such as the US, Japan, Canada and Europe, as well as faster-growing and emerging economies including Brazil, Russia, India, and ChinaServes as an essential resource for students, professors, and researchers who seek a better understanding of the interface between the pharmaceutical industry, health care systems, and society INDICE: SECTION I: PHARMACEUTICAL INDUSTRY, SOCIETY, AND GOVERNANCE 1. Pharmaceutical Regulation: The Role of Government 2. Trends in Innovation and the Business of Drug Discovery 3. Cash Flow Valley of Death: A Pitfall in Drug Discovery SECTION II: THE DRUG DISCOVERY CYCLE I: DISCOVERY AND PRECLINICAL DRUG DEVELOPMENT 4. Prediscovery Research: Challenges and Opportunities 5.  The Significance of Discovery Screening and Structure Optimization Studies 6. Preclinical In Vitro Studies - Development and Applicability 7.  Animal Utilization in Drug Development - Clinical, Legal, and Ethical Dimensions 8.  Pharmaceutical Formulation and Manufacturing Development: Strategies and Issues SECTION III  THE DRUG DISCOVERY CYCLE II: CLINICAL DEVELOPMENT 9. Clinical Development: Ethics and Realities 10.  Pharmacogenomics in Drug Discovery, Prospects and Clinical Applicability SECTION IV  THE DRUG DISCOVERY CYCLE III: AUTHORIZATION AND MARKETING 11. Patents, Exclusivities, and Evergreening Strategies 12. Drug Pricing and Control for Pharmaceutical Drugs Index

• ISBN: 978-0-12-802220-7
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 324
• Fecha Publicación: 01/03/2016
• Nº Volúmenes: 1
• Idioma: Inglés