Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action and influence over disease processes. This book examines the role of protein biosynthesis interference in Alzheimer's and other neurodegenerative conditions, cancer, and inflammatory disorders in-depth, with specific attention paid to the biochemical dynamics of tryptamine, biogenic amines, and aminoacyl-tRNA synthetases in these pathologies. Methods of regulating protein translation and interference mechanisms, including gene therapy, are presented, empowering biochemists, molecular biologists, disease researchers, and health professionals to understand the underlying factors of protein disease and improve patient outcomes. Enables biochemists, molecular biologists and disease researchers to advance disease prevention, laboratory testing, and treatment pathways for protein biosynthesis interference related disordersExamines the biochemical and molecular basis of protein biosynthesis interference in neurodegenerative disorders, cancer, and inflammatory conditions among other diseasesAnalyzes tryptamine, biogenic amines, and aminoacyl-tRNA synthetases dynamics in protein translation and possible treatment pathways regulating protein biosynthesis INDICE: 1. Early and late onset dementia is a brain-specific disease or systemic widespread disease: the tryptamine/biogenic amines/protein biosynthesis/human microbiome theory2. Human gut bacterial tryptamine pathway links Alzheimer's disease with colorectal cancer3. Immunogenic peptides of tryptophanyl-tRNA synthetase in cancer phosphosignaling4. Tryptophanyl-tRNA synthetase in organism survival
- ISBN: 978-0-12-823485-3
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 208
- Fecha Publicación: 01/11/2020
- Nº Volúmenes: 1
- Idioma: Inglés