In this first book on the topic, important key definitions and general concepts will be provided in a tutorial way. Natural product synthesis will be classified according to main biosynthetic pathways (e.g. terpenes, alkaloids, polyketides). A focus will be the biomimetic efforts towrds the total synthesis of natural products. Key features include: Biomimetic Strategies have become an every-day tool not only for chemists but also for biologists. The synthetic applications are overwhelming and there is a definite need for this book. Unifying both synthetic and biosynthetic aspects this book covers everything from organocatalysis and natural product synthesis to synthetic biology and even greenchemistry. Over 248000 hits in Google on Biomimetic Synthesis and 2000 hits in ISI Web of Knowledge. INDICE: Foreword INTRODUCTION Biomimetic Chemistry, Biomimetic Synthesis On the Structure of the Book: Reading Guidelines BIOMIMETIC SYNTHESIS OF TERPENOIDS AND POLYPRENYLATED NATURAL COMPOUNDS Key Biosynthesis Elements IsoprenoidPolyene Electrophilic Cyclizations Complex Terpenoids from Rearrangements Polyprenylated Xanthones and Phloroglucinols BIOMIMETIC SYNTHESIS OF POLYKETIDES Key Biosynthetic Elements Polyketide Assembly Mimics and Biomimetic Access to Aromatic Rings Polycyclic Aliphatic Polyketides Biomimetic Polyepoxide Openings, Polyether Natural Substances Biomimetic Electrocyclizations towards Polyketides BIOMIMETIC TOTAL SYNTHESIS OF ALKALOIDS Key Biosynthesis Elements Alkaloids Derived from Ornithine and Lysine Alkaloids Derived from Tyrosine AlkaloidsDerived from Tryptophan: Indolomonoterpenic Alkaloids Alkaloids Derived from Tryptophan: Diketopiperazine Alkaloids Alkaloids Derived from Tryptophan: Miscellaneous Indole Alkaloids Biomimetic Synthesis of Marine Manzamine-Type Alkaloids Biomimetic Synthesis of Marine Pyrrole-Imidazole and Guanidinium Alkaloids Alkaloids Derived by Amination MISCELLANEOUS NATURAL PRODUCTS Miscellaneous Biomimetic Syntheses of Natural Products Artifacts: Natural Substances Formed Spontaneously
- ISBN: 978-3-527-32580-1
- Editorial: Wiley-VCH
- Encuadernacion: Cartoné
- Páginas: 900
- Fecha Publicación: 20/04/2011
- Nº Volúmenes: 1
- Idioma: Inglés