Cancer Biomarkers: Clinical Aspects and Laboratory Determination

Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies. This title is a perfect reference for clinical pathologists, laboratory scientists, medical technologists, physicians specializing in oncology, internal medicine, family practice and transplant medicine, resident physicians, medical students, nurse practitioners and clinical chemists. Provides insights into the overall complexity that the cancer patient presents and how laboratory tests are used in the management of care Discusses current and new technologies applicable to cancer biomarker evaluation, including the use of non-traditional specimens like saliva, fluids and uterine lavage Reviews current trends in liquid biopsy and cancer biomarkers Provides a roadmap for bringing new technologies and markers from the bench to the bedside in the quest for finding the ideal tumor marker INDICE: 1. Overview of tumor markers, traditional and non-traditional (include glycans)2. Laboratory testing in pediatric cancer patients3. The adult cancer patient: overview and current laboratory testing4. Thyroglobulin measurement: its importance in monitoring and recurrence of thyroid cancer5. PSA, long term prognosis6. Monoclonal gammopathy detection and current technologies7. Liquid biopsy potential and challenges8. CAR T therapies and the management of toxicity9. Validating circulating tumor cells and cell free DNA as an LDT for use in the clinic10. Saliva as a matrix for measurement of biomarkers11. Emerging technologies in the detection and monitoring of cancer12. Oncometabolites13. Circulating cancer biomarkers: current status and future prospects

• ISBN: 978-0-12-824302-2
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 308
• Fecha Publicación: 01/06/2022
• Nº Volúmenes: 1
• Idioma: Inglés