The handbook of neuropsychiatric biomarkers, endophenotypes and genes v. III Metabolic and peripheral biomarkers

Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunities to understandthe etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues ofthe biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. New tools for biomarker-discovery Endophenotype strategy Peripheral biomarkers for neuropsychiatric disorders Neuroimaging biomarkers and endophenotypes Neurocognitive biomarkers and endophenotypes Pharmacogenetics and pharmacogenomics INDICE: I: Possible Metabolic and Peripheral Biomarkers. 1. Peripheral biomarkers in dementia and Alzheimer’s disease. 2. S100B as a potential neurochemical biomarker in a variety of neurological, neuropsychiatric and neurosurgical disorders. 3. Can the cortisol to DHEA molar ratio be used as a peripheral biomarker for schizophrenia and mood disorders? 4. Neuroactive steroid biomarkers of alcohol sensitivity and alcoholism risk. 5. Neuroendocrine markers of psychopathy. 6. Mitochondrial complex I as a possible peripheral biomarker for schizophrenia. 7. Peripheral biomarkers of excitotoxicity in neurological diseases. 8. Melatonin as a biological marker in schizophrenia. 9. Peripheral biological markers for mood disorders. 10. The diagnosis of alcoholism through the identification of biochemical markers in hair. 11. Retinoic acid signalling inneuropsychiatric disease: possible markers and treatment agents. 12. Abnormalities of inositol metabolism in lymphocytes as biomarkers for bipolar disorder. Index.

• ISBN: 978-1-4020-9837-6
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 214
• Fecha Publicación: 01/06/2009
• Nº Volúmenes: 1
• Idioma: Inglés