Functional Connectivity of the Human Brain: From Mechanisms to Clinical Applications
Rocca, Maria Assunta
Filippi, Massimo
Functional Connectivity of the Human Brain: From Mechanisms to Clinical Applications is a comprehensive review of mechanisms and analysis of methods of functional connectivity to map brain organization in healthy individuals and sick patients. Providing full coverage of the discipline for a wide audience of different research and clinical specialists, this volume begins with descriptions of mechanisms of functional connectivity and methodological approaches to quantify it, followed by a focus on how functional connectivity has been used to describe brain function in healthy people and to characterize network disruption in diseased conditions. This practical balance in book structure is suitable for readers with a technical or clinical orientation, providing background that is easy to approach for clinicians or scientists. Chapters examine fMRI and electrophysiological techniques, brain maturation, aging, and cognitive neurosciences, as well as functional connectivity in neuroinflammatory, neurodegenerative, and neuropsychiatric conditions. Future perspectives look forward to functional connectivity in multimodal analysis, artificial intelligence, and more. This book will be of use to a wide audience working on functional connectivity experiments, as well as any courses on the topic. Covers the main mechanisms of functional connectivityProvides an overview of the main methodological aspects to map brain organizationDescribes state-of-the-art achievements obtained with functional connectivity to study network functioning in healthy individuals and sick patientsDiscusses future developments in the field INDICE: 1. Functional connectivity: definition and signal origins 2. Assessing functional connectivity: the role of functional MRI and electrophysiological techniques 3. Analysis methods for functional connectivity: from seed-regions to data-driven approaches 4. Causal connections in the brain: from functional to effective connectivity 5. Exploring functional connectivity using graph theoretical analysis 6. Time-varying analysis of functional connectivity 7. The main functional networks of the brain: default-mode network and beyond 8. Trajectories of brain functional connectivity in brain maturation 9. Trajectories of brain functional connectivity in brain aging 10. Application of functional connectivity to cognitive neurosciences 11. Functional connectivity in neuroinflammatory conditions 12. Functional connectivity in neurodegenerative conditions 13. Functional connectivity in neuropsychiatric diseases 14. Current limitations in functional connectivity assessment: suggestions for analysis improvements 15. Future perspectives of functional connectivity: multimodal analysis, artificial intelligence, and more
- ISBN: 978-0-443-19099-5
- Editorial: Academic Press
- Encuadernacion: Rústica
- Páginas: 450
- Fecha Publicación: 01/06/2025
- Nº Volúmenes: 1
- Idioma: Inglés