Design and analysis of non-inferiority trials

The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Using examples from real clinical trials, the book discusses general and regulatory issues and illustrates how they affect analysis. Each chapter begins with a non-technical introduction, so the subject is easily understood by thosewithout prior knowledge of non-inferiority clinical trials. The book also provides detailed mathematical approaches along with their mathematical properties.

• ISBN: 978-1-58488-804-8
• Editorial: Chapman and Hall/CRC
• Encuadernacion: Cartoné
• Páginas: 454
• Fecha Publicación: 12/07/2011
• Nº Volúmenes: 1
• Idioma: Inglés