The book that Sakamoto proposes along with Eric Ruben will be a comprehensivemonograph on the role of protein modulation in cancer therapeutics; it will focus on targeting molecules that regulate protein stability in a variety of tumors. INDICE: Protacs chimeric molecules to target cancer causing proteins for ubiquitination and degradation.- Topors and sumoylation in cancer therapy.- Ubistatins.- Novel roteasome inhibitors.- MDM2 inhibitors.- HSP90 inhibitors in cancer therapy.- Novel proteasome inhibitors in multiple myeloma.- Novel HDAC6 inhibitor.- Histone deacetylase inhibitors in prostate cancer.- The role of ISG15 in carcinogenesis.
- ISBN: 978-0-387-69143-5
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 165
- Fecha Publicación: 04/05/2009
- Nº Volúmenes: 1
- Idioma: Inglés