Pharmacology and Pharmacotherapeutics, 26e

This book strengthens the scientific knowledge base and promotes rational thinking among students The Medical Council of India (MCI) has introduced a competency-based curriculum in 2019, which not only lays emphasis on integration with clinical and pre-clinical subjects but also clearly states subject competencies and defines domains and levels to be achieved for each of them. In addition, it is clinically oriented and gives due importance to the self-directed learning. The duration of teaching for the subject of Pharmacology in the new curriculum has been reduced to one year with additional dedicated time to revisit it in the subsequent years. This 26th edition of Pharmacology and Pharmacotherapeutics has been revised considerably to match the demands of the new curriculum. Right from its conception, this book has used an integrated approach intertwining current knowledge of pathophysiology of the disease, pharmacology of available drugs and strategies for medical management of diseases. We have made every attempt to provide up-to-date information about the drugs while focussing on the aspects relevant to their use in clinical practice. INDICE: SECTION 1: General Pharmacology 1. General Considerations and Pharmacokinetics 2. Pharmacodynamics - Drug Receptor Interactions; Adverse Drug Reactions 3. Principles of Drug Prescribing; Factors Modifying the Effects of a Drug; and Drug Interactions 4. Drug Invention, New Drug Development, and Drug Assay SECTION 2: Drugs Acting on the Central Nervous System 5. General Considerations 6. Aliphatic Alcohols 7. General Anaesthetics 8. Sedatives, Hypnotics and Pharmacotherapy of Sleep Disorders 9. Drugs Effective in Seizure Disorders 10. Opioid Analgesics and Antagonists 11. Analgesic-Antipyretics and Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) 12. Central Nervous System Stimulants, 174 13. Psychopharmacology - 1: Introduction, Antipsychotic Drugs, Pharmacotherapy of Psychosis and Psychotogenic Drugs 14. Psychopharmacology - 2: Anxiolytics, Antidepressants and Pharmacotherapy of Depression and Manic-Depressive Psychosis 15. Drug Therapy of Parkinsonism and Other Neurodegenerative Disorders SECTION 3: Local Anaesthetics 16. Cocaine, Procaine and Other Synthetic Local Anaesthetics SECTION 4: Autonomic Nervous System 17. General Considerations 18. Adrenergic Agonists and Antagonists 19. Cholinergic Drugs 20. Muscarinic Receptor Blocking Drugs; Pharmacotherapy of Bladder Dysfunction 21. Ganglion Stimulating and Blocking Drugs; Treatment of Tobacco Dependence 22. Skeletal Muscle Relaxants SECTION 5: Other Biogenic Amines and Polypeptides 23. Histamine and Antihistaminic Drugs 24. 5-Hydroxytryptamine (Serotonin), Its Agonists and Antagonists; and Treatment of Migraine 25. Angiotensin, Kinins, Leukotrienes, Prostaglandins and Cytokines SECTION 6: Drugs Used in Respiratory Disorders 26. Pharmacotherapy of Cough 27. Pharmacotherapy of Bronchial Asthma, COPD and Rhinitis SECTION 7: Cardiovascular Drugs 28. Pharmacotherapy of Cardiac Arrhythmias 29. Pharmacotherapy of Angina Pectoris, Acute MI and Peripheral Vascular Diseases 30. Pharmacotherapy of Hypertension, Pulmonary Hypertension and Orthostatic Hypotension 31. Pharmacotherapy of Heart Failure 32. Pharmacotherapy of Shock SECTION 8: Drugs Acting on Blood and Blood Forming Organs 33. Drugs and Blood Coagulation 34. Drugs Effective in Iron Deficiency and Other Related Anaemias 35. Drugs Effective in Megaloblastic Anaemias, Neutropenia and Thrombocytopenia 36. Drug-Induced Blood Dyscrasias SECTION 9: Drugs Affecting Renal Functions 37. Diuretic and Antidiuretic Drugs, and Drug-Induced Nephrotoxicity SECTION 10: Drugs Used in Disorders of the Gastrointestinal Tract 38. Appetite Stimulants, Digestants, Antiflatulents, Appetite Suppressants and Hypolipidaemic Agents 39. Emetics, Drug Therapy of Vomiting, Vertigo and Diarrhoea 40. Pharmacotherapy of Constipation 41. Pharmacotherapy of Peptic Ulcer Disease SECTION 11: Oxytocics and Uterine Relaxants 42. Pharmacology of Ergot Alkaloids, Oxytocin, Other Oxytocics and Uterine Relaxants SECTION 12: Chemotherapy 43. Sulphonamides, Trimethoprim, Cotrimoxazole, Nitrofurans and Quinolones 44. Penicillins and Other Antibiotics Effective Mainly against Gram-Positive Organisms 45. Aminoglycosides and Other Antibiotics Effective Mainly Against Gram-Negative Organisms 46. Antibiotics Effective Against Both Gram-Positive and Gram-Negative Organisms 47. Tetracyclines and Chloramphenicol 48. Antifungal Agents 49. General Principles of Chemotherapy of Infections 50. Chemotherapy of Urinary Tract Infections 51. Chemotherapy of Sexually Transmitted Diseases 52. Chemotherapy of Tuberculosis 53. Chemotherapy of Leprosy 54. Chemotherapy of Malaria 55. Chemotherapy of Amoebiasis 56. Chemotherapy of Other Protozoal Infections 57. Chemotherapy of Viral Infections 58. Chemotherapy of Helminthiases 59. Chemotherapy of Malignancy 60. Antiseptics, Disinfectants and Insecticides SECTION 13: Drugs Used in Endocrine Disorders 61. Anterior Pituitary Hormones 62. Thyroid Hormones and Antithyroid Drugs 63. Pancreatic Hormones, Antidiabetic Drugs and Pharmacotherapy of Diabetes Mellitus 64. Adrenal Cortical Steroids 65. Gonadotropins, Estrogens and Progestins 66. Antifertility Agents and Ovulation-Inducing Drugs 67. Androgens, Anabolic Steroids, Antiandrogens and Treatment of Sexual Dysfunction 68. Calcium, Phosphorus, Fluoride and Magnesium Metabolism; Parathyroid Hormone and Vitamin D; Treatment of Osteoporosis SECTION 14: Drugs Used in Common Skin and Eye Disorders 69. Pharmacotherapy of Common Skin Disorders and Skin Protectives 70. Ocular Pharmacology SECTION 15 Immunopharmacology 71. General Considerations: Vaccines and Antisera 72. Immunoglobulins, Monoclonal Antibodies, Immunosuppressants and Immunomodulators SECTION 16: Miscellaneous 73. Pharmacotherapy of Gout, Rheumatoid Arthritis and Osteoarthritis 74. Metals and Their Antagonists 75. Gases: Therapeutic and Toxic 76. Enzymes in Therapy 77. Vitamins and Antioxidants 78. Drugs, Pregnancy and the Infant Appendix Illustration Credits Index Flow Charts of Drug Classifications

• ISBN: 978-8-1312-5695-4
• Editorial: Elsevier India
• Encuadernacion: Rústica
• Páginas: 1160
• Fecha Publicación: 10/07/2020
• Nº Volúmenes: 1
• Idioma: Inglés